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1

Together we stand, apart we fall: how cell-to-cell contact/interplay provides resistance to ferroptosis

Vucetic, Milica, Daher, Boutaina, Cassim, Shamir, Meira, Willian, Pouyssegur, Jacques

Journal:

Cell Death and Disease

Year:

2020

File:

PDF, 1.47 MB

2020

2

Hypoxia: the tumor's gateway to progression along the angiogenic pathway

Christiane Brahimi-Horn, Edurne Berra, Jacques Pouysségur

Journal:

Trends in Cell Biology

Year:

2001

Language:

english

File:

PDF, 2.88 MB

english, 2001

3

ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1

Buscà, Roser, Christen, Richard, Lovern, Matthew, Clifford, Alexander M., Yue, Jia-Xing, Goss, Greg G., Pouysségur, Jacques, Lenormand, Philippe

Journal:

BMC Evolutionary Biology

Year:

2015

Language:

english

File:

PDF, 2.77 MB

english, 2015

4

Disrupting proton dynamics and energy metabolism for cancer therapy

Parks, Scott K., Chiche, Johanna, Pouysségur, Jacques

Journal:

Nature Reviews Cancer

Year:

2013

Language:

english

File:

PDF, 900 KB

english, 2013

5

Physical and Genetic Mapping of a Human Apical Epithelial Na+/H+ Exchanger (NHE3) Isoform to Chromosome 5p15.3

Steven R. Brant, Michael Bernstein, John J. Wasmuth, Eugene W. Taylor, John D. McPherson, Xiang Li, Susan Walker, Jacques Pouyssegur, Mark Donowitz, Chung-Ming Tse, Ethylin Wang Jabs

Journal:

Year:

1993

File:

PDF, 362 KB

1993

6

Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+symporters

Marchiq, Ibtissam, Pouysségur, Jacques

Journal:

Journal of Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 2.45 MB

english, 2016

7

Erk Kinases Link Pre-B Cell Receptor Signaling to Transcriptional Events Required for Early B Cell Expansion

Tomoharu Yasuda, Hideki Sanjo, Gilles Pagès, Yohei Kawano, Hajime Karasuyama, Jacques Pouysségur, Masato Ogata, Tomohiro Kurosaki

Journal:

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

8

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

Johanna Chiche, M. Christiane Brahimi-Horn, Jacques Pouysségur

Journal:

Journal of Cellular and Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 1.21 MB

english, 2010

9

Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect

Compan, Vincent, Pierredon, Sandra, Vanderperre, Benoît, Krznar, Petra, Marchiq, Ibtissam, Zamboni, Nicola, Pouyssegur, Jacques, Martinou, Jean-Claude

Journal:

Year:

2015

Language:

english

File:

PDF, 2.66 MB

english, 2015

10

Independent activation of endogenous p21-activated protein kinase-3 (PAK3) and JNK by thrombin in CCL39 fibroblasts

Kenneth C. Malcolm, Jean-Claude Chambard, Dominique Grall, Jacques Pouysségur, Ellen van Obberghen-Schilling

Journal:

Journal of Cellular Physiology

Year:

2000

Language:

english

File:

PDF, 194 KB

english, 2000

11

Structure/function studies of the epithelial isoforms of the mammalian Na+/H+exchanger gene family

Ming Tse, Sue Levine, Chris Yun, Steve Brant, Laurent T. Counillon, Jacques Pouyssegur, Mark Donowitz

Journal:

Journal of Membrane Biology

Year:

1993

Language:

english

File:

PDF, 1.65 MB

english, 1993

12

A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor

Tournaire, Roselyne, Simon, Marie-Pierre, Noble, Ferdinand le, Eichmann, Anne, England, Patrick, Pouysségur, Jacques

Journal:

Year:

2004

Language:

english

File:

PDF, 229 KB

english, 2004

13

pH control mechanisms of tumor survival and growth

Scott K. Parks, Johanna Chiche, Jacques Pouyssegur

Journal:

Journal of Cellular Physiology

Year:

2011

Language:

english

File:

PDF, 153 KB

english, 2011

14

Mutant α subunits of Gi2 inhibit cyclic AMP accumulation

Wong, Yung H., Federman, Alex, Pace, Ann M., Zachary, Ian, Evans, Tony, Pouysségur, Jacques, Bourne, Henry R.

Journal:

Year:

1991

File:

PDF, 376 KB

1991

15

Spatiotemporal regulation of the p42/p44 MAPK pathway

Véronique Volmat, Jacques Pouysségur

Journal:

Biology of the Cell

Year:

2001

Language:

english

File:

PDF, 355 KB

english, 2001

16

cDNA cloning and expression of a hamster α-thrombin receptor coupled to Ca2+ mobilization

Ulla B. Rasmussen, Valérie Vouret-Craviari, Sophie Jallat, Yasmin Schlesinger, Gilles Pagès, Andrea Pavirani, Jean-Pierre Lecocq, Jacques Pouysségur, Ellen Van Obberghen-Schilling

Journal:

Year:

1991

Language:

english

File:

PDF, 779 KB

english, 1991

17

Major contribution of MEK1 to the activation of ERK1/ERK2 and to the growth of LS174T colon carcinoma cells

Jessica Shama, Raquel Garcia-Medina, Jacques Pouysségur, Emmanuel Vial

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 532 KB

english, 2008

18

The directionality of locomotion of mouse fibroblasts: Role of cell adhesiveness

Jacques Pouysségur, Ira Pastan

Journal:

Experimental Cell Research

Year:

1979

Language:

english

File:

PDF, 682 KB

english, 1979

19

Targeting pH regulating proteins for cancer therapy–Progress and limitations

Parks, Scott K., Pouysségur, Jacques

Journal:

Seminars in Cancer Biology

Year:

2017

Language:

english

File:

PDF, 460 KB

english, 2017

20

François Lavelle (1943–2018)

Larsen, Christian, Armand, Jean-Pierre, Robert, Jacques, Verrelle, Pierre, Pouysségur, Jacques, Évrard, Serge, Harel-Bellan, Annick, Marty, Michel, Dutreix, Marie

Journal:

Bulletin du Cancer

Year:

2018

Language:

french

File:

PDF, 168 KB

french, 2018

21

α-Thrombin-induced inositol phosphate formation in go-arrested and cycling hamster lung fibroblasts: Evidence for a protein kinase C-mediated desensitization response

Gilles L'Allemain, Sonia Paris, Isabelle Magnaldo, Jacques Pouysségur

Journal:

Journal of Cellular Physiology

Year:

1986

Language:

english

File:

PDF, 1.25 MB

english, 1986

22

Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b

Ciais, Delphine, Cherradi, Nadia, Bailly, Sabine, Grenier, Emilie, Berra, Edurne, Pouyssegur, Jacques, LaMarre, Jonathan, Feige, Jean-Jacques

Journal:

Year:

2004

Language:

english

File:

PDF, 314 KB

english, 2004

23

Hypoxia-inducible factor-1α (HIF-1α) escapes O 2 -driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm

Berra, Edurne, Roux, Danièle, Richard, Darren E, Pouysségur, Jacques

Journal:

Year:

2001

Language:

english

File:

PDF, 356 KB

english, 2001

24

Role of the ERK signaling in the developing cerebral cortex

Imamura, Osamu, Seita, Ryoko, Pagès, Gilles, Pouysségur, Jacques, Satoh, Yasushi, Endo, Shogo, Takishima, Kunio

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 83 KB

english, 2010

25

Integration of a ‘proton antenna’ facilitates transport activity of the monocarboxylate transporter MCT4

Noor, Sina Ibne, Pouyssegur, Jacques, Deitmer, Joachim W., Becker, Holger M.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

26

Disrupting the ‘Warburg effect’ re-routes cancer cells to OXPHOS offering a vulnerability point via ‘ferroptosis’-induced cell death

Ždralević, Maša, Vučetić, Milica, Daher, Boutaina, Marchiq, Ibtissam, Parks, Scott K., Pouysségur, Jacques

Journal:

Advances in Biological Regulation

Year:

2017

Language:

english

File:

PDF, 793 KB

english, 2017

27

Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response

Cassim, Shamir, Pouyssegur, Jacques

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 1.26 MB

english, 2019

28

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling : Delivered on 24 October 2002 at the 28th FEBS Meeting in Istanbul

Jacques Pouysségur, Philippe Lenormand

Journal:

Year:

2003

Language:

english

File:

PDF, 275 KB

english, 2003

29

Isolation and immunological characterization of a glucose-regulated fibroblast cell surface glycoprotein and its nonglycosylated precursor

Pouysségur, Jacques, Yamada, Kenneth M.

Journal:

Year:

1978

Language:

english

File:

PDF, 9.55 MB

english, 1978

30

Tumor hypoxia and metabolism – Towards novel anticancer approaches

Chiche, Johanna, Ricci, Jean-Ehrland, Pouysségur, Jacques

Journal:

Annales d'Endocrinologie

Year:

2013

File:

PDF, 514 KB

2013

31

Chinese hamster serotonin (5-HT) type 2 receptor cDNA sequence

Chambard, Jean-Claude, Van Obberghen Schilling, Ellen, Haslam, Richard J., Vouret, Valérie, Pouysségur, Jacques

Journal:

Nucleic Acids Research

Year:

1990

Language:

english

File:

PDF, 104 KB

english, 1990

32

Hypoxia protects against the cell death triggered by oxovanadium–galactomannan complexes in HepG2 cells

Meyenberg Cunha-de Padua, Monique, Noleto, Guilhermina Rodrigues, de Oliveira Petkowicz, Carmen Lucia, Cadena, Silvia Maria Suter Correia, Bost, Frédéric, Pouysségur, Jacques, Mazure, Nathalie M.

Journal:

Cellular & Molecular Biology Letters

Year:

2019

Language:

english

File:

PDF, 1.96 MB

english, 2019

33

A Transport System for 2-Keto-3-deoxy-d-gluconate Uptake in Escherichia coli K12 : Biochemical and Physiological Studies in Whole Cells

Alain E. Lagarde, Jacques M. Pouysségur, François R. Stoeber

Journal:

Year:

1973

Language:

english

File:

PDF, 1.21 MB

english, 1973

34

Mitogen-potentiating action and binding characteristics of insulin and insulin-like growth factors in Chinese hamster fibroblasts

Ellen Van Obberghen-Schilling, Jacques Pouysségur

Journal:

Experimental Cell Research

Year:

1983

Language:

english

File:

PDF, 2.28 MB

english, 1983

35

HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1α degradation

Edurne Berra, Darren E Richard, Emmanuel Gothié, Jacques Pouysségur

Journal:

Year:

2001

Language:

english

File:

PDF, 352 KB

english, 2001

36

Mitogenic Effects of Fibroblast Growth Factors in Cultured Fibroblastsa : Interaction with the G-Protein-Mediated Signaling Pathways

SONIA PARIS, JACQUES POUYSSÉGUR

Journal:

Annals of the New York Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 486 KB

english, 1991

37

Role of Cell Surface Carbohydrates and Proteins in Cell Behavior: Studies on the Biochemical Reversion of an N-acetylglucosamine-Deficient Fibroblast Mutant

Jacques Pouysségur, Mark Willingham and Ira Pastan

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 1.31 MB

english, 1977

38

Glucose Depletion Accounts for the Induction of Two Transformation-Sensitive Membrane Proteins in Rous Sarcoma Virus-Transformed Chick Embryo Fibroblasts

Robert P. C. Shiu, Jacques Pouyssegur and Ira Pastan

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 1.29 MB

english, 1977

39

PHD2 Mutation and Congenital Erythrocytosis with Paraganglioma

Ladroue, Charline, Carcenac, Romain, Leporrier, Michel, Gad, Sophie, Le Hello, Claire, Galateau-Salle, Françoise, Feunteun, Jean, Pouysségur, Jacques, Richard, Stéphane, Gardie, Betty

Journal:

Boston Medical and Surgical Journal

Year:

2008

Language:

english

File:

PDF, 712 KB

english, 2008

40

HIF-1α mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour

Gaëlle Cane, Amandine Ginouvès, Sandrine Marchetti, Roser Buscà, Jacques Pouysségur, Edurne Berra, Paul Hofman, Valérie Vouret-Craviari

Journal:

Cellular Microbiology

Year:

2010

Language:

english

File:

PDF, 355 KB

english, 2010

41

Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin

Chambard, Jean Claude, Paris, Sonia, L'Allemain, Gilles, Pouysségur, Jacques

Journal:

Year:

1987

File:

PDF, 518 KB

1987

42

Harnessing the hypoxia-inducible factor in cancer and ischemic disease

M. Christiane Brahimi-Horn, Jacques Pouysségur

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 588 KB

english, 2007

43

Mechanical allodynia but not thermal hyperalgesia is impaired in mice deficient for ERK2 in the central nervous system

Yukiko Otsubo, Yasushi Satoh, Mitsuyoshi Kodama, Yoshiyuki Araki, Maiko Satomoto, Eiji Sakamoto, Gilles Pagès, Jacques Pouysségur, Shogo Endo, Tomiei Kazama

Journal:

Year:

2012

Language:

english

File:

PDF, 1.37 MB

english, 2012

44

Functional expression of the human growth factor-activatable sodium/hydrogen ion antiporter in baculovirus-infected cells

Fafournoux, Pierre, Ghysdael, Jacques, Sardet, Claude, Pouyssegur, Jacques

Journal:

Year:

1991

Language:

english

File:

PDF, 2.33 MB

english, 1991

45

Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia

Mazure, Nathalie M., Pouysségur, Jacques

Journal:

Year:

2009

Language:

english

File:

PDF, 736 KB

english, 2009

46

Hypoxia and cellular metabolism in tumour pathophysiology

Parks, Scott K., Cormerais, Yann, Pouysségur, Jacques

Journal:

The Journal of Physiology

Year:

2017

Language:

english

File:

PDF, 1.04 MB

english, 2017

47

The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code

Vučetić, Milica, Cormerais, Yann, Parks, Scott K., Pouysségur, Jacques

Journal:

Frontiers in Oncology

Year:

2017

Language:

english

File:

PDF, 1.21 MB

english, 2017

48

Adenylate cyclase in a fibroblast mutant defective in glycolipid and glycoprotein synthesis

ANDERSON, WAYNE B., JAWORSKI, CYNTHIA J., GALLO, MARIA, PASTAN, IRA, POUYSSÉGUR, JACQUES

Journal:

Year:

1978

File:

PDF, 203 KB

1978

49

The Cytoplasmic Domain of the Na+/H+Exchangers (NHEs) Dictates the Nature of the Hormonal Response: Behavior of a Chimeric Human NHE1/Trout βNHE Antiporter

Franck Borgese, Murielle Malapert, Bruno Fievet, Jacques Pouyssegur and Rene Motais

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 999 KB

english, 1994

50

Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters

Tsuji, Tokuji, Kurokawa, Yayoi, Chiche, Johanna, Pouysségur, Jacques, Sato, Hiroshi, Fukuzawa, Hideya, Nagao, Masaya, Kambe, Taiho

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 3.04 MB

english, 2017

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